rickets, osteoporosis, and osteomalacia). Vitamin D deficiency is a cause of hyperparathyroidism and diseases related to impaired bone metabolism (e.g. (This article belongs to the Section Clinical Nutrition).

Vitamin D plays a major role in calcium and phosphorus homeostasis. Cholecalciferol, unlike calcifediol, guarantees an exact dosage in IU (International. A small proportion of the 25(OH)D is further hydroxylated in the kidney, under direct regulation by parathyroid hormone and ionised calcium levels, to form the biologically-active calcitropic hormone 1,25-dihydroxyvitamin D. In the liver, vitamin D is hydroxylated to give 25(OH)D which also circulates as a complex with VDBP. Explore innovation opportunities for including vitamin.

Having the right amount of vitamin D, calcium, and. Vitamin D is stored in adipose tissue and enters the circulation bound to vitamin D binding protein (VDBP) and albumin. Latest Evidence and Effects of Vitamin D3 (cholecalciferol)- Drug Interactions. Vitamin D ( ergocalciferol -D2, cholecalciferol -D3, alfacalcidol) is a fat -soluble vitamin that helps your body absorb calcium and phosphorus. Approximately 10 – 20 % of vitamin D is supplied through nutritional intake. Main vitamin D sources are: UV exposure from sun which leads to Cholecalciferol production in the upper layers of the skin, foods such as fish, shellfish, mushrooms, vitamin D fortified foods (e.g. Of the two major forms Ergocalciferol (D2) and Cholecalciferol (D3), only vitamin D3 is synthesised by the body. Vitamin D is a fat-soluble steroid pro-hormone.

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